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Article

Mechanisms of mutant genes in spina bifida: a review of implications from animal models.

Pediatric neurosurgery - 1 Jan 1995

George T M, McLone D G

Abstract excerpt

Spina bifida (spinal neural tube defects) has been shown to be caused by an abnormality in closure of the neural tube. Basic scientific research has rapidly progressed in experimental embryology and molecular genetics to give new insights into the pathogenesis of defective neural tube closure. The chick and the mouse have proved to be the best animal models for study because of similarities to human neurulation....

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PMID: 8688348
DOI: 10.1159/000120966

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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