Article
Multiple-sited interaction of caldesmon with Ca(2+)-calmodulin.
The Biochemical journal - 1 Jun 1996
Huber P A, El-Mezgueldi M, Grabarek Z, Slatter D A, Levine B A, Marston S B
Abstract excerpt
The binding of Ca(2+)- and Ba(2+)-calmodulin to caldesmon and its functional consequence was investigated with three different calmodulin mutants. Two calmodulin mutants have pairs of cysteine residues substituted and oxidized to a disulphide bond in either the N- or C-terminal lobe (C41/75 and C...
Topics
- Adenosine Triphosphatases
- Amino Acid Sequence
- Animals
- Binding Sites
- Calcium
- Calmodulin
- Calmodulin-Binding Proteins
- Cattle
- Chickens
- Cross-Linking Reagents
- Electrophoresis, Polyacrylamide Gel
- Ethyldimethylaminopropyl Carbodiimide
- Magnetic Resonance Spectroscopy
- Molecular Sequence Data
- Mutation
- Peptide Fragments
- Sheep
- Spectrometry, Fluorescence