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Article

Ca2+ binding in proteins of the calmodulin superfamily: cooperativity, electrostatic contributions and molecular mechanisms.

Ciba Foundation symposium - 1 Jan 1991

Forsén S, Linse S, Drakenberg T, Kördel J, Akke M, Sellers P, Johansson C, Thulin E, Andersson I, Brodin P

Abstract excerpt

In a large number of intracellular regulatory proteins of the calmodulin superfamily a pair of closely interacting helix-loop-helix Ca2+ binding sites ('EF hands') constitute the functional unit--an arrangement that enables cooperative binding. We have recently made detailed experimental studies of the binding of Ca2+ ions to calmodulin, its tryptic fragments TR1C and TR2C (which each constitute a globular domain...

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PMID: 1667634
DOI: 10.1002/9780470514146.ch14

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Ca2+ binding in proteins of the calmodulin superfamily: cooperativity, electrostatic contributions and molecular mechanisms.PMID 1667634Read ↗

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