Article
Oligonucleotide arrays: new concepts and possibilities.
Bio/technology (Nature Publishing Company) - 1 Nov 1994
Chetverin A B, Kramer F R
Abstract excerpt
Advances in solid-phase oligonucleotide synthesis and hybridization techniques have led to an incipient technology based on the use of oligonucleotide arrays. The inclusion of a large number of oligonucleotide probes within a single array greatly reduces the cost of their synthesis and allows thousands of hybridizations to be carried out simultaneously. The range of potential applications of oligonucleotide...
Topics
- Alleles
- Base Sequence
- Genome, Human
- Humans
- Molecular Sequence Data
- Nucleic Acid Hybridization
- Oligonucleotide Probes
- Polymerase Chain Reaction