Article
Dendrimeric coating of glass slides for sensitive DNA microarrays analysis.
Nucleic acids research - 15 Aug 2003
Le Berre Véronique, Trévisiol Emmanuelle, Dagkessamanskaia Adilia, Sokol Serguei, Caminade Anne-Marie, Majoral Jean Pierre, Meunier Bernard, François Jean
Abstract excerpt
Successful use and reliability of microarray technology is highly dependent on several factors, including surface chemistry parameters and accessibility of cDNA targets to the DNA probes fixed onto the surface. Here, we show that functionalisation of glass slides with homemade dendrimers allow production of more sensitive and reliable DNA microarrays. The dendrimers are nanometric structures of size-controlled...
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