Article
Reduction-triggered red fluorescent probes for dual-color detection of oligonucleotide sequences.
Organic & biomolecular chemistry - 21 Feb 2009
Furukawa Kazuhiro, Abe Hiroshi, Wang Jin, Uda Miwako, Koshino Hiroyuki, Tsuneda Satoshi, Ito Yoshihiro
Abstract excerpt
We have developed a new red fluorogenic compound derived from naphthorhodamine for a reduction-triggered fluorescence probe to sense oligonucleotides. The fluorogenic reaction between naphthorhodamine azide derivatives and reducing reagents such as triphenylphosphine (TPP) on the DNA target does not use any enzyme or reagent, and fluoresces at 650 nm. The probes were used for dual color detection of a single...
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