Article
[Detection of genetic alterations in sporadic breast tumors].
Gynakologisch-geburtshilfliche Rundschau - 1 Jan 1995
Schmutzler R K, Homann A, Bierhoff E, Wiestler O D, von Daimling A, Krebs D
Abstract excerpt
OBJECTIVE: Loss of heterozygosity (LOH) indicates the existence of tumor suppressor genes (TSG) in the affected chromosomal loci. In order to uncover the involvement of such genes, we analyzed LOH in different chromosomal regions of sporadic breast carcinomas. MATERIAL AND METHOD: 47 breast cance...
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