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Article

Gene and chromosomal alterations in sporadic breast cancer: correlation with histopathological features and implications for genesis and progression.

Breast cancer (Tokyo, Japan) - 1 Jan 2009

Tsuda Hitoshi

Abstract excerpt

A number of gene and chromosome alterations have been identified in sporadic breast carcinomas, and their clinical implications have been investigated. Changes in proto-oncogenes and tumor-suppressor genes, e.g., HER2, p53, and E-cadherin, and various numerical and structural chromosome alterations are strongly correlated with histological type and grade in breast carcinomas. The amount of information on these...

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PMID: 19472036
DOI: 10.1007/s12282-009-0124-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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