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[Study of BRCA1 and BRCA2 gene mutations in human sporadic breast cancers].

Zhonghua wai ke za zhi [Chinese journal of surgery] - 1 Apr 2007

Zhang Hai-Tian, Lu Yun-Fei, Zeng Jian, Lin Jian, Liao Qing-Hua, Wan Fu-Qiang

Abstract excerpt

OBJECTIVE: To detect the mutations of BRCA1 and BRCA2 in sporadic breast cancer and study the relationship between BRCA1 and BRCA2 mutations and breast cancer. METHODS: Breast cancer tissues of 144 patients and breast tissues of 30 cases of healthy people who were treated from December 2000 to September 2005 were studied. DNA was extracted by the phenol-chloroform method. Fragments of exon 2, exon 3, exon 5, exon...

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Apoptosis Regulatory Proteins
Blotting, Western
BRCA1 Protein
BRCA2 Protein
Breast Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

DNA Mutational Analysis

Polymerase Chain Reaction

Polymorphism, Single-Stranded Conformational

Source

Identifiers

PMID: 17686308

Genes

BRCA1
BRCA2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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