Article
Ontogeny and immunohistochemical localization of thymus-dependent and thymus-independent RT6+ cells in the rat.
The American journal of pathology - 1 Jun 1996
Waite D J, Appel M C, Handler E S, Mordes J P, Rossini A A, Greiner D L
Abstract excerpt
RT6 is a cell surface alloantigen that identifies a regulatory subset of peripheral T cells in the rat. Diabetes-prone BB rats are deficient in peripheral RT6+ T cells and develop spontaneous autoimmune insulin-dependent diabetes mellitus. Diabetes-resistant BB rats have normal numbers of RT6+ T...
Topics
- ADP Ribose Transferases
- Animals
- Animals, Newborn
- Antigens, Differentiation, T-Lymphocyte
- Blotting, Western
- Female
- Flow Cytometry
- Histocompatibility Antigens
- Immunoblotting
- Immunohistochemistry
- Intestinal Mucosa
- Isoantibodies
- Lymphoid Tissue
- Male
- Membrane Glycoproteins
- Phenotype
- Rats
- Rats, Inbred BB