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Article

CD8+ T-cells are required for adoptive transfer of the BB rat diabetic syndrome.

Diabetes - 1 Mar 1993

Edouard P, Hiserodt J C, Plamondon C, Poussier P

Abstract excerpt

LGLs with NK activity account for the majority of BB rat PBLs expressing CD8, and it has been suggested that these LGL/NK cells are involved in the pathogenesis of the BB rat diabetic syndrome. By using a recently developed mouse MoAb, 3.2.3, specific for rat LGL, we demonstrate that BB and WF rat LGLs are phenotypically and functionally similar. To directly assess the role of LGLs in the development of diabetes...

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Share to Antibodies, Monoclonal
Share to Diabetes Mellitus, Type 1
Share to Immunotherapy, Adoptive

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Rats, Inbred BB

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Share to T-Lymphocytes, Cytotoxic

Source

Identifiers

PMID: 8432409
DOI: 10.2337/diab.42.3.390

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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