CD8+ T-cells are required for adoptive transfer of the BB rat diabetic syndrome.

doi:10.2337/diab.42.3.390

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Article

CD8+ T-cells are required for adoptive transfer of the BB rat diabetic syndrome.

Diabetes - 1 Mar 1993

Edouard P, Hiserodt J C, Plamondon C, Poussier P

Abstract excerpt

LGLs with NK activity account for the majority of BB rat PBLs expressing CD8, and it has been suggested that these LGL/NK cells are involved in the pathogenesis of the BB rat diabetic syndrome. By using a recently developed mouse MoAb, 3.2.3, specific for rat LGL, we demonstrate that BB and WF ra...

Topics

Animals
Antibodies, Monoclonal
Diabetes Mellitus, Type 1
Female
Immunotherapy, Adoptive
Male
Phenotype
Rats
Rats, Inbred BB
Rats, Inbred WF
Syndrome
T-Lymphocytes, Cytotoxic

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