Article
Transcription stimulates homologous recombination in mammalian cells.
Molecular and cellular biology - 1 Sept 1990
Nickoloff J A, Reynolds R J
Abstract excerpt
Transcription stimulates homologous recombination in Saccharomyces cerevisiae and has been implicated in the control of recombinational events during the development of mammalian immune systems. Here, we describe a plasmid-based system in which an inducible promoter from the mouse mammary tumor virus is located upstream of heteroallelic neomycin genes carried on two plasmids. Pairs of plasmids are introduced into...
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