Relative frequencies of homologous recombination between plasmids introduced into DNA repair-deficient and other mammalian somatic cell lines.

doi:10.1007/BF01232460

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Article

Relative frequencies of homologous recombination between plasmids introduced into DNA repair-deficient and other mammalian somatic cell lines.

Somatic cell and molecular genetics - 1 Jul 1990

Wahls W P, Moore P D

Abstract excerpt

Twelve mammalian somatic cell lines, some of them DNA damage-sensitive mutants paired with their respective wild-type parental lines, were assayed for their ability to catalyze extrachromosomal, intermolecular homologous recombination between pSV2neo plasmid recombination substrates. All of the s...

Topics

Agammaglobulinemia
Animals
Ataxia Telangiectasia
Cell Line
Cricetinae
DNA Repair
Genetic Variation
Humans
Mice
Mutation
Plasmids
Recombination, Genetic
Transfection

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