Article
The homologue of mammalian SPC12 is important for efficient signal peptidase activity in Saccharomyces cerevisiae.
The Journal of biological chemistry - 12 Jul 1996
Fang H, Panzner S, Mullins C, Hartmann E, Green N
Abstract excerpt
The multisubunit signal peptidase catalyzes the cleavage of signal peptides and the degradation of some membrane proteins within the endoplasmic reticulum (ER). The only subunit of this enzyme functionally examined to date, yeast Sec11p, is related to signal peptidase I from bacteria. Since bacte...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Dogs
- Frameshift Mutation
- Fungal Proteins
- Hydrolysis
- Membrane Proteins
- Molecular Sequence Data
- Peptide Hydrolases
- Phenotype
- Protein Sorting Signals