Article
Differential responsiveness of a splice variant of the human type I interferon receptor to interferons.
The Journal of biological chemistry - 7 Jun 1996
Cook J R, Cleary C M, Mariano T M, Izotova L, Pestka S
Abstract excerpt
Chinese hamster ovary cells containing the yeast artificial chromosome F136C5 (alphaYAC) respond to all type I human interferons including IFN-alphaA, IFN-beta, and IFN-omega. The alphaYAC contains at least two genes encoding interferon-alpha receptor (IFN-alphaR) chains that are required for response to type I human interferons: Hu-IFN-alphaR1 and Hu-IFN-alphaR2. We previously isolated a splice variant of the...
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