Both variant forms of interferon-alpha4 gene (IFNA4a and IFNA4b) are present in the human population.

doi:10.1089/jir.1997.17.559

Article

Both variant forms of interferon-alpha4 gene (IFNA4a and IFNA4b) are present in the human population.

Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research - 1 Sept 1997

Hussain M, Gill D S, Liao M J

Abstract excerpt

Alpha interferons (IFN-alpha) are a class of cytokines with various activities that are used as therapeutic agents for treatment of cancer and viral and immune disorder diseases. At least 13 IFN-alpha genes and 1 IFN-alpha pseudogene have been identified, which are clustered on human chromosome 9...

Topics

Antineoplastic Agents
Antiviral Agents
DNA Fragmentation
Gene Amplification
Genetic Variation
Humans
Interferon-alpha
Restriction Mapping

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