Article
Mutant U5A cells are complemented by an interferon-alpha beta receptor subunit generated by alternative processing of a new member of a cytokine receptor gene cluster.
The EMBO journal - 16 Oct 1995
Lutfalla G, Holland S J, Cinato E, Monneron D, Reboul J, Rogers N C, Smith J M, Stark G R, Gardiner K, Mogensen K E
Abstract excerpt
The cellular receptor for the alpha/beta interferons contains at least two components that interact with interferon. The ifnar1 component is well characterized and a putative ifnar2 cDNA has recently been identified. We have cloned the gene for ifnar2 and show that it produces four different transcripts encoding three different polypeptides that are generated by exon skipping, alternative splicing and...
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