Article
Interaction between a putative mechanosensory membrane channel and a collagen.
Science (New York, N.Y.) - 19 Jul 1996
Liu J, Schrank B, Waterston R H
Abstract excerpt
The degenerin family of proteins in Caenorhabditis elegans is homologous to subunits of the mammalian amiloride-sensitive epithelial sodium channels. Mutations in nematode degenerins cause cell death, probably because of defects in channel function. Genetic evidence was obtained that the unc-105 gene product represents a degenerin homolog affecting C. elegans muscles and that this putative channel interacts with...
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