Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Loss of constitutional heterozygosity in chromosome 10 in human glioblastoma.

Acta neuropathologica - 1 Jan 1990

Watanabe K, Nagai M, Wakai S, Arai T, Kawashima K

Abstract excerpt

Gene deletion of chromosome 10 in 11 tumor tissues removed from nine patients with malignant glioma (seven glioblastomas and two malignant astrocytomas) was investigated. Loss of heterozygosity was found in four of the seven (57%) cases with glioblastoma, whereas heterozygosity was preserved in t...

Topics

Adolescent
Adult
Aged
Alleles
Child
Child, Preschool
Chromosome Deletion
Chromosomes, Human, Pair 10
DNA
Female
Glioma
Heterozygote
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Middle Aged

Polymorphism, Restriction Fragment Length

Source

Identifiers

PMID: 1975968
DOI: 10.1007/BF00294641

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1975968-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Loss of constitutional heterozygosity in chromosome 10 in human glioblastoma.PMID 1975968Read ↗

Loss of heterozygosity for 10q loci in human gliomas.Semantic proximity Read ↗

Loss of heterozygosity in malignant gliomas involves at least three distinct regions on chromosome 10Semantic proximity Read ↗

Loss of heterozygosity of chromosome 10p in human gliomas.Semantic proximity Read ↗

Loss of heterozygosity for alleles on chromosome 10 in human brain tumours.Semantic proximity Read ↗

Deletion mapping of chromosome 10 in human glioma.Semantic proximity Read ↗

Loss of heterozygosity analysis in malignant gliomas.Semantic proximity Read ↗

Loss of heterozygosity on chromosomes 10q, 9p, 17p and 13q in malays with malignant glioma.Semantic proximity Read ↗

p53 mutation and loss of heterozygosity on chromosomes 17 and 10 during human astrocytoma progression.Semantic proximity Read ↗

Analysis of loss of heterozygosity for chromosome 10 in patients with malignant astrocytic tumors: correlation with patient age and survivalSemantic proximity Read ↗

Allelotype of human malignant astrocytoma.Semantic proximity Read ↗

p53 mutation, EGFR gene amplification and loss of heterozygosity on chromosome 10, 17 p in human gliomas.Semantic proximity Read ↗

Identification of a human homolog of the Drosophila neuralized gene within the 10q25.1 malignant astrocytoma deletion region.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.