Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Loss of heterozygosity for 10q loci in human gliomas.

Genes, chromosomes & cancer - 1 Jul 1992

Rasheed B K, Fuller G N, Friedman A H, Bigner D D, Bigner S H

Abstract excerpt

Cytogenetic and RFLP studies have shown that chromosome 10 is frequently lost in tumor cells from glioblastomas, suggesting that a suppressor gene important in tumorigenesis is present on this chromosome. Forty-one tumors were examined for loss of heterozygosity at 23 loci on chromosome 10 to determine the smallest common deletion interval on this chromosome. Seven tumors did not lose heterozygosity for any of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain Neoplasms
Share to Chromosome Deletion
Share to Alleles

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 10

Share to DNA Probes

Share to Genetic Markers

Share to Glioma

Share to Polymorphism, Restriction Fragment Length

Source

Identifiers

PMID: 1384665
DOI: 10.1002/gcc.2870050111

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Loss of heterozygosity for 10q loci in human gliomas.PMID 1384665Read ↗

Loss of heterozygosity of chromosome 10p in human gliomas.Semantic proximity Read ↗

Loss of heterozygosity in malignant gliomas involves at least three distinct regions on chromosome 10Semantic proximity Read ↗

Loss of constitutional heterozygosity in chromosome 10 in human glioblastoma.Semantic proximity Read ↗

Deletion mapping of chromosome 10 in human glioma.Semantic proximity Read ↗

Loss of heterozygosity for alleles on chromosome 10 in human brain tumours.Semantic proximity Read ↗

Frequent loss of heterozygosity for markers on chromosome arm 10q in chondrosarcomas.Semantic proximity Read ↗

Loss of heterozygosity on chromosomes 10q, 9p, 17p and 13q in malays with malignant glioma.Semantic proximity Read ↗

Allelic losses of chromosome 10 in glioma tissues detected by quantitative single-strand conformation polymorphism analysis.Semantic proximity Read ↗

Loss of alleles in brain tumours: distribution and correlations with clinical course.Semantic proximity Read ↗

Acquisition of the glioblastoma phenotype during astrocytoma progression is associated with loss of heterozygosity on 10q25-qter.Semantic proximity Read ↗

Analysis of loss of heterozygosity for chromosome 10 in patients with malignant astrocytic tumors: correlation with patient age and survivalSemantic proximity Read ↗

Allelic losses on chromosomes 14, 10, and 1 in atypical and malignant meningiomas: a genetic model of meningioma progression.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.