Article
A candidate gene for the amnionless gastrulation stage mouse mutation encodes a TRAF-related protein.
Developmental biology - 10 Jul 1996
Wang X, Bornslaeger E A, Haub O, Tomihara-Newberger C, Lonberg N, Dinulos M B, Disteche C M, Copeland N, Gilbert D J, Jenkins N A, Lacy E
Abstract excerpt
We report the identification of a new recessive prenatal lethal insertional mutation, amnionless (amn). amn mutant embryos first appear abnormal during the Early Streak stage, between E6.5 and E7.0, when they initiate mesoderm production. Subsequently, the amn mutants become developmentally arrested between the Mid and Late Streak stages of gastrulation and they die and are resorbed between E9.5 and E10.5. While...
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