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Article

The Emerging Role of TRAF7 in Tumor Development.

Journal of cellular physiology - 1 Jun 2017

Zotti Tiziana, Scudiero Ivan, Vito Pasquale, Stilo Romania

Abstract excerpt

The seven members of the tumor necrosis factor receptor (TNF-R)-associated factor (TRAF) family of intracellular proteins were originally discovered and characterized as signaling adaptor molecules coupled to the cytoplasmic regions of receptors of the TNF-R superfamily. Functionally, TRAFs act both as a scaffold and/or enzymatic proteins to regulate activation of mitogen-activated protein kinases (MAPKs) and...

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Source

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Identifiers

PMID: 27808423
DOI: 10.1002/jcp.25676
PMCID: PMC5347962

Genes

TRAF7
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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