Article
Use of specific ELISA for the detection of antibodies directed against p53 protein in patients with hepatocellular carcinoma.
Journal of clinical pathology - 1 Apr 1996
Ryder S D, Rizzi P M, Volkmann M, Metivier E, Pereira L M, Galle P R, Naoumov N V, Zentgraf H, Williams R
Abstract excerpt
AIMS: To analyse the significance of antibodies to p53 protein as a serological marker for changes in p53 gene expression in patients with hepatocellular carcinoma. METHODS: Thirty eight patients with hepatocellular carcinoma, 19 showing accumulation of p53 protein by immunohistochemistry and 19...
Topics
- Antibodies, Neoplasm
- Biomarkers, Tumor
- Carcinoma, Hepatocellular
- Enzyme-Linked Immunosorbent Assay
- Genes, p53
- Humans
- Immunoenzyme Techniques
- Liver Neoplasms
- Mutation
- Neoplasm Proteins
- Tumor Suppressor Protein p53
- alpha-Fetoproteins
