Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Use of specific ELISA for the detection of antibodies directed against p53 protein in patients with hepatocellular carcinoma.

Journal of clinical pathology - 1 Apr 1996

Ryder S D, Rizzi P M, Volkmann M, Metivier E, Pereira L M, Galle P R, Naoumov N V, Zentgraf H, Williams R

Abstract excerpt

AIMS: To analyse the significance of antibodies to p53 protein as a serological marker for changes in p53 gene expression in patients with hepatocellular carcinoma. METHODS: Thirty eight patients with hepatocellular carcinoma, 19 showing accumulation of p53 protein by immunohistochemistry and 19 having no accumulation, were studied. The presence of anti-p53 was tested using a novel ELISA utilising a recombinant...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers, Tumor
Share to Carcinoma, Hepatocellular

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Enzyme-Linked Immunosorbent Assay

Share to Genes, p53

Share to Liver Neoplasms

Share to Mutation

Share to Neoplasm Proteins

Share to Tumor Suppressor Protein p53

Source

Open in PubMed Open full text

Identifiers

PMID: 8655704
DOI: 10.1136/jcp.49.4.295
PMCID: PMC500454

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Use of specific ELISA for the detection of antibodies directed against p53 protein in patients with hepatocellular carcinoma.PMID 8655704Read ↗

The humoral immune response to p53 in patients with hepatocellular carcinoma is specific for malignancy and independent of the alpha-fetoprotein status.Semantic proximity Read ↗

p53 antibodies in the sera of lung cancer patients: comparison with p53 mutation in the tumour tissue.Semantic proximity Read ↗

p53 genetic alterations, protein expression and autoantibodies in human colorectal carcinoma: A comparative study.Semantic proximity Read ↗

Prognostic significance of serum anti-p53 antibody in patients with hepatocellular carcinoma.Semantic proximity Read ↗

Assessment of the potential diagnostic value of serum p53 antibody for cancer: a meta-analysis.Semantic proximity Read ↗

Serum anti-p53 antibodies as a useful marker for prognosis of gastric carcinoma.Semantic proximity Read ↗

Enzyme-linked immunosorbent assay for p53 in gastrointestinal malignancy: comparison with immunohistochemistry.Semantic proximity Read ↗

p53 gene mutation, tumor p53 protein overexpression, and serum p53 autoantibody generation in patients with breast cancer.Semantic proximity Read ↗

Clinical utility of anti-p53 auto-antibody: systematic review and focus on colorectal cancer.Semantic proximity Read ↗

Immunohistochemical Determination of p53 Protein Overexpression for Predicting p53 Gene Mutations in Hepatocellular Carcinoma: A Meta-Analysis.Semantic proximity Read ↗

p53 protein accumulation in European hepatocellular carcinoma is not always dependent on p53 gene mutation.Semantic proximity Read ↗

Clinical significance of serum and ascitic p53 autoantibodies in epithelial ovarian carcinoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.