Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Frequent NF2 gene transcript mutations in sporadic meningiomas and vestibular schwannomas.

American journal of human genetics - 1 Jun 1994

Lekanne Deprez R H, Bianchi A B, Groen N A, Seizinger B R, Hagemeijer A, van Drunen E, Bootsma D, Koper J W, Avezaat C J, Kley N

Abstract excerpt

The gene for the hereditary disorder neurofibromatosis type 2 (NF2), which predisposes for benign CNS tumors such as vestibular schwannomas and meningiomas, has been assigned to chromosome 22 and recently has been isolated. Mutations in the NF2 gene were found in both sporadic meningiomas and vestibular schwannomas. However, so far only 6 of the 16 exons of the gene have been analyzed. In order to extend the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to DNA Mutational Analysis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Molecular Sequence Data

Share to Mutation

Share to Polymerase Chain Reaction

Share to Polymorphism, Restriction Fragment Length

Share to RNA, Messenger

Share to Transcription, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 7911002
PMCID: PMC1918179

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Frequent NF2 gene transcript mutations in sporadic meningiomas and vestibular schwannomas.PMID 7911002Read ↗

Predominant occurrence of somatic mutations of the NF2 gene in meningiomas and schwannomas.Semantic proximity Read ↗

Screening for mutations in the neurofibromatosis type 2 (NF2) gene in sporadic meningiomas.Semantic proximity Read ↗

Somatic NF2 gene mutations in familial and non-familial vestibular schwannoma.Semantic proximity Read ↗

Mutations of the neurofibromatosis type 2 gene and lack of the gene product in vestibular schwannomas.Semantic proximity Read ↗

Combined molecular genetic studies of chromosome 22q and the neurofibromatosis type 2 gene in central nervous system tumors.Semantic proximity Read ↗

Analysis of the neurofibromatosis type 2 gene in different human tumors of neuroectodermal origin.Semantic proximity Read ↗

Analysis of the neurofibromatosis 2 gene reveals molecular variants of meningioma.Semantic proximity Read ↗

Familial schwannomatosisSemantic proximity Read ↗

Mutations in transcript isoforms of the neurofibromatosis 2 gene in multiple human tumour types.Semantic proximity Read ↗

Molecular Genetics of Neurofibromatosis 2 and Related Tumors (Acoustic Neuroma and Meningioma)<sup>a</sup>Semantic proximity Read ↗

Mutational spectrum of the NF2 gene: a meta-analysis of 12 years of research and diagnostic laboratory findings.Semantic proximity Read ↗

Neuropathology and Molecular Genetics of Neurofibromatosis 2 and Related TumorsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.