Article
Characteristics of Japanese alcoholics with the atypical aldehyde dehydrogenase 2*2. I. A comparison of the genotypes of ALDH2, ADH2, ADH3, and cytochrome P-4502E1 between alcoholics and nonalcoholics.
Alcoholism, clinical and experimental research - 1 Feb 1996
Nakamura K, Iwahashi K, Matsuo Y, Miyatake R, Ichikawa Y, Suwaki H
Abstract excerpt
We examined the genotypes of the aldehyde dehydrogenase (ALDH)-2, alcohol dehydrogenase (ADH)-2, ADH3, and P-4502E1 loci of 53 alcoholics and 97 nonalcoholics. All of the subjects fulfilled the DSM-III-R criteria for alcohol dependence. The control group consisted of 97 subjects who were either h...
Topics
- Adult
- Alcohol Dehydrogenase
- Alcoholism
- Aldehyde Dehydrogenase
- Aldehyde Dehydrogenase, Mitochondrial
- Alleles
- Cytochrome P-450 CYP2E1
- Cytochrome P-450 Enzyme System
- Ethnicity
- Female
- Gene Expression Regulation, Enzymologic
