Article
[Genotypes of alcohol dehydrogenase and aldehyde dehydrogenase and their significance for alcohol sensitivity].
Nihon rinsho. Japanese journal of clinical medicine - 1 Feb 1993
Shibuya A
Abstract excerpt
Genotypes of alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) loci were determined, using allele specific oligonucleotides. Gene frequencies of ADH2(1) and ADH2(2) were 0.29 and 0.71, respectively, in the Japanese control group. No significant difference was found in the ADH2 genotyp...
Topics
- Alcohol Dehydrogenase
- Alcoholic Intoxication
- Aldehyde Dehydrogenase
- Alleles
- Amino Acid Sequence
- DNA Probes
- Gene Frequency
- Genotype
- Humans
- Liver Diseases, Alcoholic
- Molecular Sequence Data
- Mutation
- Polymorphism, Genetic
- Racial Groups
