Article
Alcohol and aldehyde dehydrogenase polymorphisms in men with type I and Type II alcoholism.
The American journal of psychiatry - 1 May 2005
Chai Young-Gyu, Oh Dong-Yul, Chung Eun Kee, Kim Gil Sook, Kim Leen, Lee Yu-Sang, Choi Ihn-Geun
Abstract excerpt
OBJECTIVE: The authors examined the genetic polymorphisms of alcohol dehydrogenase 2 and 3 (ADH2 and ADH3) and aldehyde dehydrogenase (ALDH2) in patients diagnosed as having Cloninger's type I or type II alcoholism. METHOD: Seventy-two alcoholic men and 38 nonalcoholic, healthy men were tested for the distribution of genotypes and alleles of ADH2, ADH3, and ALDH2. Forty-eight of the alcoholic men had type I...
Topics
- Alcohol Dehydrogenase
- Alcoholism
- Aldehyde Dehydrogenase
- Gene Frequency
- Genotype
- Humans
- Korea
- Male
- Middle Aged
- Polymorphism, Genetic
- Sex Factors
