Article
High incidence of ADH2*1/ALDH2*1 genes among Japanese alcohol dependents and patients with alcoholic liver disease.
Hepatology (Baltimore, Md.) - 1 Feb 1996
Tanaka F, Shiratori Y, Yokosuka O, Imazeki F, Tsukada Y, Omata M
Abstract excerpt
In an attempt to clarify the genetic factors in alcoholism among the Japanese, polymorphism of alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) genes has been investigated. Genetic polymorphism of ADH2/ALDH2 in 66 cases of normal subjects, 90 cases of alcohol dependent, and 31 patien...
Topics
- Adult
- Aged
- Alcohol Dehydrogenase
- Alcoholism
- Aldehyde Dehydrogenase
- Asian People
- Base Sequence
- DNA Primers
- Female
- Gene Frequency
- Genotype
- Humans
- Isoenzymes
- Japan
- Liver Diseases, Alcoholic
- Male
- Middle Aged
- Molecular Sequence Data