Article
Yeast RSP5 and its human homolog hRPF1 potentiate hormone-dependent activation of transcription by human progesterone and glucocorticoid receptors.
Molecular and cellular biology - 1 Jun 1996
Imhof M O, McDonnell D P
Abstract excerpt
We have developed a system in Saccharomyces cerevisiae in which agonist-dependent transcriptional activity of the human progesterone receptor (hPR) is elevated to the point that it compromises cell growth. Screens for suppressors of this phenotype led to the demonstration that RSP5 is involved in...
Topics
- Base Sequence
- DNA Primers
- Endosomal Sorting Complexes Required for Transport
- Fungal Proteins
- Humans
- In Vitro Techniques
- Ligases
- Molecular Sequence Data
- Mutation
- Receptors, Glucocorticoid
- Receptors, Progesterone
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Transcription Factors
- Transcriptional Activation
- Ubiquitin-Protein Ligase Complexes
- Ubiquitin-Protein Ligases