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Article

Phylogenetic and preliminary phenotypic analysis of yeast PAQR receptors: potential antifungal targets.

Journal of molecular evolution - 1 Oct 2011

Villa Nancy Y, Moussatche Patricia, Chamberlin Stephen G, Kumar Anuj, Lyons Thomas J

Abstract excerpt

Proteins belonging to the Progestin and AdipoQ Receptor (PAQR) superfamily of membrane bound receptors are ubiquitously found in fungi. Nearly, all fungi possess two evolutionarily distinct paralogs of PAQR protein, which we have called the PQRA and PQRB subtypes. In the model fungus Saccharomyces cerevisiae, these subtypes are represented by the Izh2p and Izh3p proteins, respectively. S. cerevisiae also...

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Identifiers

PMID: 22009226
DOI: 10.1007/s00239-011-9462-3
PMCID: PMC3236824

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