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Overexpression of two transcriptional factors, Kin28 and Pog1, suppresses the stress sensitivity caused by the rsp5 mutation in Saccharomyces cerevisiae.

FEMS microbiology letters - 1 Dec 2007

Demae Mika, Murata Yoshinori, Hisano Mirei, Haitani Yutaka, Shima Jun, Takagi Hiroshi

Abstract excerpt

Rsp5 is an essential and multi-functional E3 ubiquitin ligase in Saccharomyces cerevisiae. The Ala401Glu rsp5 mutant, which is hypersensitive to various stresses, was isolated previously. To understand the function of Rsp5 in stress responses, suppressor genes whose overexpression allows rsp5(A401E) cells to grow at a high temperature were screened. The KIN28 and POG1 genes, encoding a subunit of the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 17986087
DOI: 10.1111/j.1574-6968.2007.00947.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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