Article
A protein complex containing Tho2, Hpr1, Mft1 and a novel protein, Thp2, connects transcription elongation with mitotic recombination in Saccharomyces cerevisiae.
The EMBO journal - 1 Nov 2000
Chávez S, Beilharz T, Rondón A G, Erdjument-Bromage H, Tempst P, Svejstrup J Q, Lithgow T, Aguilera A
Abstract excerpt
Transcription-induced recombination has been reported in all organisms from bacteria to mammals. We have shown previously that the yeast genes HPR1 and THO2 may be keys to the understanding of transcription-associated recombination, as they both affect transcription elongation and hyper-recombina...
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