Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Functional analysis of histones H2A and H2B in transcriptional repression in Saccharomyces cerevisiae.

Molecular and cellular biology - 1 Jun 1996

Recht J, Dunn B, Raff A, Osley M A

Abstract excerpt

The presence of H2A-H2B dimers in nucleosomes can inhibit the binding of transcription factors to chromatin templates. To study the roles of histones H2A and H2B in transcriptional repression in vivo, mutant forms of these histones were analyzed in two different assay systems. Two repression domains were identified in H2A. One domain includes residues that fall in the beginning of the H2A-H2B dimerization region,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to Binding Sites
Share to DNA Primers

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Molecular Sequence Data

Share to Mutation

Share to Promoter Regions, Genetic

Share to Saccharomyces cerevisiae

Share to Transcription, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 8649361
DOI: 10.1128/MCB.16.6.2545
PMCID: PMC231244

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functional analysis of histones H2A and H2B in transcriptional repression in Saccharomyces cerevisiae.PMID 8649361Read ↗

Evidence that Spt2/Sin1, an HMG-like factor, plays roles in transcription elongation, chromatin structure, and genome stability in Saccharomyces cerevisiae.Semantic proximity Read ↗

A new class of histone H2A mutations in Saccharomyces cerevisiae causes specific transcriptional defects in vivo.Semantic proximity Read ↗

Separation-of-function mutation in HPC2, a member of the HIR complex in S. cerevisiae, results in derepression of the histone genes but does not confer cryptic TATA phenotypes.Semantic proximity Read ↗

Mutations in the SPT4, SPT5, and SPT6 genes alter transcription of a subset of histone genes in Saccharomyces cerevisiae.Semantic proximity Read ↗

Regulation of gene transcription by the histone H2A N-terminal domain.Semantic proximity Read ↗

Patterning chromatin: form and function for H2A.Z variant nucleosomes.Semantic proximity Read ↗

A highly conserved region within H2B is important for FACT to act on nucleosomes.Semantic proximity Read ↗

Sif2p interacts with Sir4p amino-terminal domain and antagonizes telomeric silencing in yeast.Semantic proximity Read ↗

Spt10-dependent transcriptional activation in Saccharomyces cerevisiae requires both the Spt10 acetyltransferase domain and Spt21.Semantic proximity Read ↗

The role of Sas2, an acetyltransferase homologue of Saccharomyces cerevisiae, in silencing and ORC function.Semantic proximity Read ↗

Set2-catalyzed methylation of histone H3 represses basal expression of GAL4 in Saccharomyces cerevisiae.Semantic proximity Read ↗

Specific functions for the fission yeast Sirtuins Hst2 and Hst4 in gene regulation and retrotransposon silencing.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.