Article
Patterning chromatin: form and function for H2A.Z variant nucleosomes.
Current opinion in genetics & development - 1 Apr 2006
Raisner Ryan M, Madhani Hiten D
Abstract excerpt
Although many histone variants are specific to higher eukaryotes, the H2A variant H2A.Z has been conserved during eukaryotic evolution. Genetic studies have demonstrated roles for H2A.Z in antagonizing gene-silencing, chromosome stability and gene activation. Biochemical work has identified a conserved chromatin-remodeling complex responsible for H2A.Z deposition. Recent studies have shown that two H2A.Z...
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