Article
Effects of mutationally activated Ha-ras on c-fos expression kinetics in rat tracheal epithelial cells.
Molecular carcinogenesis - 1 Jun 1996
Hubbard F C, Cosma G, Garte S J
Abstract excerpt
The rat tracheal implant model was used to characterize the role of activated Ha-ras in the neoplastic progression of heterogeneous rat tracheal epithelial (RTE) cell populations. An activated Ha-ras-containing cell line, RTE 2-2, and its subclone, RTE 2-2n, which possesses only Ha-ras proto-oncogene alleles, were studied to determine whether activated ras could interact with the downstream signal transduction...
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