Article
Mutations at three sites in the Escherichia coli 23S ribosomal RNA binding region for protein L11 cause UGA-specific suppression and conditional lethality.
Nucleic acids symposium series - 1 Jan 1995
Murgola E J, Xu W, Arkov A L
Abstract excerpt
A single nucleotide change, G to A, at nucleotide position 1093 of E. coli 23S ribosomal RNA was found to cause UGA-specific suppression (D.K. Jemiolo, F.T. Pagel and E.J. Murgola, Proc. Natl. Acad. Sci. USA, in press). To obtain new kinds of UGA-specific suppressors in 23S rRNA, we used segment-...
Topics
- Bacterial Proteins
- Base Sequence
- Binding Sites
- Codon, Terminator
- Escherichia coli
- Mutagenesis, Site-Directed
- Peptide Chain Termination, Translational
- Phenotype
- Point Mutation
- RNA, Ribosomal, 23S
- Ribosomal Proteins
- Suppression, Genetic
- Temperature