Functional effects of mutating the closing GxA base-pair of a conserved hairpin loop in 23 S ribosomal RNA.

doi:10.1006/jmbi.1996.0649

Back to search

Article

Functional effects of mutating the closing GxA base-pair of a conserved hairpin loop in 23 S ribosomal RNA.

Journal of molecular biology - 6 Dec 1996

Xu W, Murgola E J

Abstract excerpt

Recently, Draper and co-workers solved the structure of a hexanucleotide hairpin loop that is conserved in large subunit ribosomal RNAs. (In Escherichia coli, the hexanucleotide consists of nucleotides 1093 to 1098, in the GTPase center of 23 S rRNA.) A major feature of that structure is a G1093x...

Topics

Base Composition
Base Sequence
Conserved Sequence
Escherichia coli
Guanosine
Molecular Sequence Data
Nucleic Acid Conformation
Phenotype
Point Mutation
Polyribosomes
RNA, Ribosomal, 23S
Suppression, Genetic

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.