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Article

Functional effects of mutating the closing GxA base-pair of a conserved hairpin loop in 23 S ribosomal RNA.

Journal of molecular biology - 6 Dec 1996

Xu W, Murgola E J

Abstract excerpt

Recently, Draper and co-workers solved the structure of a hexanucleotide hairpin loop that is conserved in large subunit ribosomal RNAs. (In Escherichia coli, the hexanucleotide consists of nucleotides 1093 to 1098, in the GTPase center of 23 S rRNA.) A major feature of that structure is a G1093xA1098 base-pair that closes the loop. Our laboratory reported previously the isolation of the mutation G1093A and its...

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PMID: 8969293
DOI: 10.1006/jmbi.1996.0649

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