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Article

Cooperative assembly of proteins in the ribosomal GTPase centre demonstrated by their interactions with mutant 23S rRNAs.

Nucleic acids research - 11 Jul 1995

Rosendahl G, Douthwaite S

Abstract excerpt

The ribosomal protein L11 binds to the region of 23S rRNA associated with the GTPase-dependent steps of protein synthesis. Nucleotides 1054-1107 within this region of the Escherichia coli 23S rRNA gene were mutagenized with bisulphite. Twenty point mutations (G-->A and C-->T transitions) and numerous multiple mutations were generated. Expression of mutant 23S rRNAs in vivo shows that all the mutations detectably...

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Identifiers

PMID: 7630717
DOI: 10.1093/nar/23.13.2396
PMCID: PMC307043

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