Article
Formation and metabolism of histone mRNAs with mutant 3' ends formed by snRNA termination signals.
Nucleic acids symposium series - 1 Jan 1995
Ingledue T, Ramamurthy L, Wortman J R, Kay B K, Marzluff W F
Abstract excerpt
Histone mRNAs are the only non-polyadenylated mRNAs, ending in a conserved 26 nt sequence which can form a stem-loop. It has not been possible to make histone mRNAs with mutant stem-loops since most mutations in the stem-loop interfere with the 3' processing reaction. The snRNA genes transcribed by RNA polymerase II form their 3' ends by transcription termination directed by a signal which is located entirely 3'...
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