Changes in the stem-loop at the 3' terminus of histone mRNA affects its nucleocytoplasmic transport and cytoplasmic regulation.

doi:10.1093/nar/22.22.4660

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Article

Changes in the stem-loop at the 3' terminus of histone mRNA affects its nucleocytoplasmic transport and cytoplasmic regulation.

Nucleic acids research - 11 Nov 1994

Williams A S, Ingledue T C, Kay B K, Marzluff W F

Abstract excerpt

The stem-loop structure at the 3' end of replication-dependent histone mRNA is required for efficient pre-mRNA processing, localization of histone mRNA to the polyribosomes, and regulation of histone mRNA degradation. A protein, the stem-loop binding protein (SLBP), binds the 3' end of histone mRNA and is thought to mediate some or all of these processes. A mutant histone mRNA with two nucleotide changes in the...

Topics

Animals
Base Sequence
Biological Transport
CHO Cells
Conserved Sequence
Cricetinae
Cytoplasm
Histones
Mice
Microinjections
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Nucleic Acid Conformation

Oocytes

RNA, Messenger

RNA-Binding Proteins

Transfection

Xenopus

Source

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Identifiers

PMID: 7984415
DOI: 10.1093/nar/22.22.4660
PMCID: PMC308515

Genes

SLBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7984415-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Changes in the stem-loop at the 3' terminus of histone mRNA affects its nucleocytoplasmic transport and cytoplasmic regulation.PMID 7984415Read ↗

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