Article
Expression of GCAP1 and GCAP2 in the retinal degeneration (rd) mutant chicken retina.
FEBS letters - 29 Apr 1996
Semple-Rowland S L, Gorczyca W A, Buczylko J, Helekar B S, Ruiz C C, Subbaraya I, Palczewski K, Baehr W
Abstract excerpt
We cloned the guanylate cyclase activating proteins, GCAP1 and GCAP2, from chicken retina and examined their expression in normal and predegenerate rdlrd chicken retina. Northern analyses show that the amounts of the single transcripts encoding GCAP1 and GCAP2 are reduced to about 70% of normal levels in rdlrd retina. Western analyses reveal that GCAP2 levels appear normal in this retina, while GCAP1 levels are...
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