Article
Cone cell survival and downregulation of GCAP1 protein in the retinas of GC1 knockout mice.
Investigative ophthalmology & visual science - 1 Oct 2004
Coleman Jason E, Zhang Yan, Brown Gary A J, Semple-Rowland Susan L
Abstract excerpt
PURPOSE: To examine the spatial and temporal characteristics of cone cell survival and the expression of guanylate cyclase-activating proteins (GCAPs) in the guanylate cyclase (GC)-1 knockout (KO) mouse retina. METHODS: Immunohistochemical analyses with peanut agglutinin and an antibody specific for cone transducin were used to examine cone cell survival in the GC1 KO retina at 4, 5, 9, 16, and 24 weeks of age....
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