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Article

Identification of Gene Expression Changes Associated with the Progression of Retinal Degeneration in therd1Mouse

23 Aug 2004

Abstract excerpt

PURPOSE: One approach to gaining insight into the biological pathways contributing to rod and cone photoreceptor death is to identify patterns of gene expression changes. In the present study, a custom retinal microarray was developed to analyze the rd1 mouse, a well-characterized animal model of human retinal degeneration. METHODS: A microarray was constructed containing cDNA fragments corresponding to genes...

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PMID: 15326104
DOI: 10.1167/iovs.03-1184

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