Article
Diet, acetylator phenotype, and risk of colorectal neoplasia.
Lancet (London, England) - 18 May 1996
Roberts-Thomson I C, Ryan P, Khoo K K, Hart W J, McMichael A J, Butler R N
Abstract excerpt
BACKGROUND: Inherited or acquired differences in metabolic pathways that activate or inactivate dietary carcinogens may influence the risk of developing cancer. A polymorphism in N-acetyltransferase classified people into fast and slow acetylators. This enzyme catalyses the formation of mutagenic products from foodstuffs, especially cooked meat and fish. Some data suggest that fast acetylators are at higher risk...
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