Article
Selection of a precore mutant after vertical transmission of different hepatitis B virus variants is correlated with fulminant hepatitis in infants.
Journal of medical virology - 1 Dec 1995
Bahn A, Hilbert K, Martiné U, Westedt J, von Weizsäcker F, Wirth S
Abstract excerpt
The incidence of perinatal transmission of hepatitis B virus (HBV) depends on the HBeAg/anti-HBe status of the mother. While children of HBeAg-positive mothers have a 90% probability of acquiring a chronic hepatitis B virus carrier state, babies of anti-HBe-positive mothers are more likely to dev...
Topics
- Adolescent
- Adult
- Base Sequence
- DNA, Viral
- Female
- Hepatitis B
- Hepatitis B e Antigens
- Hepatitis B virus
- Humans
- Infectious Disease Transmission, Vertical
- Molecular Sequence Data
- Mutation
- Pregnancy
- Sequence Analysis