Article
The double edged sword of the immune response: mutational analysis of a murine anti-pneumococcal, anti-DNA antibody.
The Journal of clinical investigation - 15 May 1996
Putterman C, Limpanasithikul W, Edelman M, Diamond B
Abstract excerpt
Anti-double-stranded (ds) DNA antibodies are not only an important diagnostic marker for SLE, but also play an important role in tissue injury. Microbial antigen may be a stimulus for the production of these antibodies. We isolated 99D.7E, an IgG2b monoclonal antibody from a nonautoimmune BALB/c...
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