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Article

Lupus anti-DNA autoantibodies cross-react with a glomerular structural protein: a case for tissue injury by molecular mimicry

1 Apr 2001

Abstract excerpt

Anti-DNA autoantibodies are the hallmark of human and murine systemic lupus erythematosus (SLE), an autoimmune rheumatic disease of unknown etiology. Some of these antibodies are believed to be pathogenic for kidney tissue and to initiate immune glomerulonephritis. However, the mechanisms by which anti-DNA antibodies participate in tissue injury remain controversial. We have studied the in vivo pathogenicity of...

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PMID: 11298348
DOI: 10.1002/1521-4141(200104)31:4<1221::aid-immu1221>3.0.co;2-p

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Source receipt: pubmed, retrieved 7 Sept 2026.

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