Article
The inflammatory response in pediatric biliary disease: macrophage phenotype and distribution.
Journal of pediatric surgery - 1 Jan 1996
Tracy T F, Dillon P, Fox E S, Minnick K, Vogler C
Abstract excerpt
PURPOSE: Extrahepatic biliary obstruction in infants and children leads to ductal hyperplasia and portal fibrosis. Inflammatory mediators responsible for increased cellular proliferation and matrix deposition are hypothesized to result from the intrahepatic recruitment and activation of lymphocytes and macrophages (M phi). The authors previously showed components of this mechanism in studies that demonstrated...
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