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Article

Alterations in tumor necrosis factor-alpha expression by hepatic macrophages following acute cholestatic liver injury.

Shock (Augusta, Ga.) - 1 Feb 1996

Fox E S, Tracy T F

Abstract excerpt

The liver is unique for its large resident macrophage (HM phi) population as a potential source of immunoregulatory cytokines. The present study was designed to determine HM phi function in a rat model of cholestasis (CBDL). Northern blot analysis of TNF-alpha mRNA showed a profound difference in...

Topics

Acute Disease
Animals
Blotting, Northern
Cholestasis
Dose-Response Relationship, Drug
Kupffer Cells
Lipopolysaccharides
Male
Phenotype
RNA, Messenger
Rats
Rats, Sprague-Dawley
Tumor Necrosis Factor-alpha

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 8705387
DOI: 10.1097/00024382-199602000-00005

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8705387-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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