Functional expression of Escherichia coli endonuclease IV in apurinic endonuclease-deficient yeast.

doi:10.1074/jbc.271.13.7368

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Article

Functional expression of Escherichia coli endonuclease IV in apurinic endonuclease-deficient yeast.

The Journal of biological chemistry - 29 Mar 1996

Ramotar D, Demple B

Abstract excerpt

Saccharomyces cerevisiae Apn1 and Escherichia coli endonuclease IV are homologous enzymes that initiate the repair of abasic (AP) sites or oxidative DNA strand breaks. Yeast lacking Apn1 (apn1-) are hypersensitive to simple alkylating agents (which produce many AP sites) and to oxidants and displ...

Topics

Base Sequence
Cloning, Molecular
DNA Primers
DNA Repair
DNA-(Apurinic or Apyrimidinic Site) Lyase
Deoxyribonuclease IV (Phage T4-Induced)
Drug Resistance, Microbial
Escherichia coli
Escherichia coli Proteins
Galactose
Gene Deletion

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Gene Expression

Genes, Bacterial

Genes, Fungal

Genetic Complementation Test

Glucose

Kinetics

Lyases

Source

Open in PubMed

Identifiers

PMID: 8631759
DOI: 10.1074/jbc.271.13.7368

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8631759-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Functional expression of Escherichia coli endonuclease IV in apurinic endonuclease-deficient yeast.PMID 8631759Read ↗

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